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last updated 01-03-2011

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2011 Journal Club

Date Presenter Paper
Jan 12 Dr Krawetz Identification of Candidate IgG Biomarkers for Alzheimer’s Disease via Combinatorial Library Screening
Jan 19 Graham Integrative Analysis of the Caenorhabditis elegans Genome by the modENCODE Project
Jan 26 Aletheia The majority of total nuclear-encoded non-ribosomal RNA in a human cell is 'dark matter' un-annotated RNA
Feb 09 Nancy* Selective chemical labeling reveals the genome-wide distribution of 5-hydroxymethylcytosine
Feb 16 Daniel Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
Feb 23 Graham Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction
March 02 Luan* Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
March 09 Nancy* Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of a-Ketoglutarate-Dependent Dioxygenases
March 16 Victor Genome-wide profiling of forum domains in Drosophila melanogaster
March 23 Ester DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors
March 30 Tung* Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
April 06 Shihong De novo assembly and analysis of RNA-seq data
April 20 Graham Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm
April 27 Edward Chromatin Organization in Sperm May Be the Major Functional Consequence of Base Composition Variation in the Human Genome
May 11 Victor Genome-wide analysis reveals novel molecular features of mouse recombination hotspots
May 18 Asmita* TET1 and hydroxymethylcytosine in transcription andDNAmethylation fidelity
June 8 Kathrin DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria
June 15 Ester Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
June 22 Richard* Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
June 29 Edward Computational methods for transcriptome annotation and quantification using RNA-seq
July 06 Tung* PubMed and beyond: a survey of web tools for searching biomedical literature
July 13 Graham Determinants of nucleosome organization in primary human cells
July 20 Shihong Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA
Sept 28 Graham The three-dimensional folding of the a-globin gene domain reveals formation of chromatin globules
Oct 05 Graham Sperm Methylation Profiles Reveal Features of Epigenetic Inheritance and Evolution in Primates
Nov 09 Shihong Preconception omega-3 fatty acid supplementation of adult male mice with a history of developmental 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure prevents preterm birth in unexposed female partners
Nov16 16 Graham The three-dimensional folding of the a-globin gene domain reveals formation of chromatin globules
Nov 23 Luan* Human metabolic individuality in biomedical and pharmaceutical research
Dec 14 Graham Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

*: from Dr Ruden's lab

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