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last updated 03-26-2010

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2010 Journal Club

Date Presenter Paper
Jan 13 Graham Determination of the in vivo structural DNA loop organization in the genomic region of the rat albumin locus by means of a topological approach
Jan 20 Fred Genome-wide profiling of salt fractions maps physical properties of chromatin
Jan 27 Rich Paternal Control of Embryonic Patterning in Arabidopsis thaliana
Feb 17 Claudia Nucleosomes are preferentially positioned at exons in somatic and sperm cells
Feb 24 Fred H2A.Z-Containing Nucleosomes Mediate the Thermosensory Response in Arabidopsis
March 03 Edward Variability in gene expression underlies incomplete penetrance
March 10 Graham RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis
March 24 Shihong IntOGen: integration and data mining of multidimensional oncogenomic data
March 31 Claudia MicroRNA Activity Is Suppressed in Mouse Oocytes AND MicroRNA Function Is Globally Suppressed in Mouse Oocytes and Early Embryos
April 7 Dr Ruden The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain AND Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
April 14 Tung *
Local DNA Topography Correlates with Functional Noncoding Regions of the Human Genome
April 21 Luan * A Drosophila Model of Friedreich's Ataxia and Autophagic Heart Disease
April 28 Graham Chromatin signature of embryonic pluripotency is established during genome activation
May 05 Shihong Analyzing ĺomics data using hierarchical models
May 12 Graham Heritable Individual-Specific and Allele-Specific Chromatin Signatures in Humans
May 19 Nancy * Hsp90 prevents phenotypic variation by suppressing the mutagenic activity of transposons
May 26 Edward RNA-seq: An assessment of technical reproducibility and comparison with gene expression arrays
June 02 Luan * Limitations in a frataxin knockdown cell model for Friedreich ataxia in a high-throughput drug screen
June 09 Graham Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
June 16 Steve Proper regulation of a sperm-specific cis-nat-siRNA is essential for double fertilization in Arabidopsis
June 23 Aletheia The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth
June 30 Gram Epigenetics as a unifying principle in the aetiology of complex traits and diseases
July 07 Adele Comparative transcriptomics of Arabidopsis sperm cells
July 14 Luan * Direct detection of DNA methylation during single-molecule, real-time sequencing
July 21 Edward PRDM9 Is a Major Determinant of Meiotic Recombination Hotspots in Humans and Mice
Aug 04 Graham Short RNAs Are Transcribed from Repressed Polycomb Target Genes and Interact with Polycomb Repressive Complex-2
Aug 11 Nancy * Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
Aug 18 Adele Ontological evaluation of transcriptional differences between sperm of infertile males and fertile donors using microarray analysis.
Aug 25 Edward The MicroArray Quality Control (MAQC)-IIII study of common practices for the development and validation of microarray-based predictive models
Sept 01 Shihong Discovery and characterization of chromatin states for systematic annotation of the human genome
Sept 15 Luan * A Drosophila Chromatin Factor Interacts With the piRNA Mechanism in Niche Cells to Regulate Germline Stem Cell Self-renewal
Sept 29 Graham PTIP Promotes Chromatin Changes Critical for Immunoglobulin Class Switch Recombination
Oct 06 Aletheia Role of translation by mitochondrial-type ribosomes during sperm capacitation: An analysis based on a proteomic approach
Nov 10 Graham Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage
Dec 01 Graham Quantitative analysis of the transcription control mechanism
Dec 08 Edward Biases in Illumina transcriptome sequencing caused by random hexamer priming AND Modeling non-uniformity in short-read rates in RNA-Seq data
Dec 15 Luan * Drosophila Piwi Functions in Hsp90-Mediated Suppression of Phenotypic Variation
Dec 22 Daniel Epigenetic Reprogramming in Plant and Animal Development

*: from Dr Ruden's lab












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