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2013 Journal Club

Presenting Date Presenter Paper
Jan 09 Edward NGS analyses by visualization with Trackster
Jan 16 Wen* NGS class report
Jan 23 Meritxell MicroRNA-181 Regulates CARM1 and Histone Aginine Methylation to Promote Differentiation of Human Embryonic Stem Cells
Jan 30 Graham RNA-Guided Human Genome Engineering via Cas9 AND Multiplex Genome Engineering Using CRISPR/Cas Systems
Feb 06 Yu Review: Sex chromosome evolution and the expression of sex-specific genes in the placenta. AND Retrotransposons and germ cells: reproduction, death, and diversity
Feb 13 Meritxell Chromatin signatures and retrotransposon profiling in mouse embryos reveal regulation of LINE-1 by RNA
Feb 20 Arko* Tip60 HAT Activity Mediates APP Induced Lethality and Apoptotic Cell Death in the CNS of a Drosophila Alzheimer’s Disease Model
March 13 Graham Disclosure of a structural milieu for the proximity ligation reveals the elusive nature of an active chromatin hub
March 20 Luan* Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans
April 03 Wen* Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
April 10 Jain** Posttranscriptional activation of gene expression in Xenopus laevis oocytes by microRNA-protein complexes (microRNPs)
April 24 Meritxell Novel Small Noncoding RNAs in Mouse Spermatozoa, Zygotes and Early Embryos AND A novel class of tRNA-derived small RNAs extremely enriched in mature mouse sperm
May 1 Akshata*** B7h (ICOS-L) Maintains Tolerance at the Fetomaternal Interface
May 8 Arko* DNA Oxidation as Triggered by H3K9me2 Demethylation Drives Estrogen-Induced Gene Expression
May 22 Videos (1) Using deep whole-genome sequencing to understand the role of non-coding genetic variation in complex developmental disease. AND (2) Large noncoding RNAs can localize to regulatory DNA targets by exploiting the three-dimensional architecture of the genome. AND (3) A general approach to account for technical noise in single-cell RNA-seq experiments.
June 19 Meritxell Circular RNAs are a large class of animal RNAs with regulatory potency
June 19 Tohid*** ß-catenin activation contributes to the pathogenesis of adenomyosis through epithelial-mesenchymal transition
July 03 Graham Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa
July 10 Chandni** One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
July 17 Marica Arenas*** Direct Proteomic Quantification of the Secretome of Activated Immune Cells
July 24 Wen Qu* An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
Aug 7 Meritxell Comparative analysis of RNA sequencing methods for degraded or low-input samples
Aug 14 Graham Polypurine-repeat-containing RNAs: a novel class of long non-coding RNA in mammalian cells
Aug 21 Wang Luan A persistent RNA DNA hybrid formed by transcription of the Friedreich ataxia triplet repeat in live bacteria, and by T7 RNAP in vitro
Aug 28 Wen Qu A Novel Alternative RNA Splicing Code that is Conserved in Animals and Plants
Sept 5 Dr. Sascha Drewlo Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsia
Sept 12 Ed A Differential Wiring Analysis of Expression Data Correctly Identifies the Gene Containing the Causal Mutation)
Sept 19 Arko Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)

*: from Ruden's lab
**: from Armant's lab
***: from Gomez-Lopez's lab

Previous Journal Clubs:

Journal club 2012

Journal club 2011

Journal club 2010

Last updated: Jan 02, 2013

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